Cannabis users needed up to twice the sedation for medical procedures
(CNN) People who regularly use cannabis may need two times the level of sedation required by nonusers when undergoing medical procedures, a small scale canada goose uk shop study finds. Fentanyl, midazolam and propofol, three sedation drugs commonly used during endoscopic procedures, were compared in the research.
Marijuana has gained popularity around the globe in recent years due, in part, to changing laws.
How does increasing cannabis use affect medical care? Researchers at Community Hospital in Grand Junction, Colorado, explored one small area of medical care: sedation. canada goose jacket outlet They examined the medical records of 250 patients who received endoscopic procedures between January canada goose outlet store 1, 2016, and canada goose store canada goose outlet uk December 31, 2017 years after the state legalized recreational marijuana in 2012.
Comparing cannabis users to nonusers, they found that patients who reported smoking or using edibles on a daily or weekly canada goose basis required 14% more fentanyl, 20% more midazolam and 220% more propofol to achieve optimum sedation canada goose outlet parka for routine procedures, including colonoscopies. For example, it took 13.83 milligrams of propofol, Canada Goose Jackets on average, for 225 nonusers to float into canada goose outlet reviews unconsciousness, compared with 44.81 milligrams canada goose outlet nyc needed, on average, by 25 cannabis users. Asking questions about cannabis use during canada goose outlet intake be an important canada goose outlet store uk tool for planning patient care and assessing both medication needs and possible risks during endoscopic procedures, they wrote.
Too few study participants
Dr. Roderic Eckenhoff,a professor buy canada goose jacket cheap of anesthesia at the University of Pennsylvania, said the study is interesting but lacked rigor. would consider this a pilot study that maybe somebody should pick up on and do a more complete trial, said Eckenhoff, who was not involved in the https://www.baertakreation.de research.
One factor that bothered him was that the study was retrospective: The researchers simply examined medical records and compared whatever amount of sedation was used for each patient instead of controlling exact amounts of sedation and comparing the effects.
What is considered depends a lot on canada goose coats the individual providers and surgeons involved, Eckenhoff canada goose factory outlet said. This combined with a small number just 25 of cannabis using patients makes the results tenuous at best, he said.
Similar results have not been seen in previous research, he said: if you give someone propofol for a canada goose outlet online uk long time, they get buy canada goose jacket a little tolerant to it, but not by canada goose black friday sale 200%. Although upward of 200% may be I be surprised if that held up in a bigger study, he said.
Finally, he noted that patients are not always reliable and don necessarily tell their doctors about else that Canada Goose sale they take, and cheap canada goose this canada goose outlet online may have influenced the results: people who use marijuana also take other drugs recreationally.